Trulicity (Dulaglutide): Uses, Dosage, Side Effects, and More

What is Trulicity?

Trulicity (dulaglutide) is an injectable prescription medication used to improve blood sugar control in adults with type 2 diabetes. It belongs to a class of drugs called GLP-1 receptor agonists, which work by stimulating insulin release, slowing digestion, and reducing appetite.

Approved by the FDA and EMA, Trulicity is also proven to lower the risk of major cardiovascular events (like heart attack or stroke) in people with type 2 diabetes and existing heart disease.

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How Does Trulicity Work?

Trulicity mimics the effects of the GLP-1 hormone, which helps regulate blood sugar by:
✔ Increasing insulin secretion (when blood sugar is high)
✔ Reducing glucagon release (a hormone that raises blood sugar)
✔ Slowing stomach emptying (leading to prolonged fullness)
✔ Promoting weight loss (a beneficial side effect for many users)

Because it is a once-weekly injection, Trulicity offers convenience compared to daily diabetes medications.

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Trulicity Dosage & Administration

Trulicity comes in pre-filled pens with four dosage strengths:

• 0.75 mg (starting dose for most patients)

• 1.5 mg

• 3 mg

• 4.5 mg (maximum dose)

How to Inject Trulicity:

1. Choose an injection site (abdomen, thigh, or upper arm).

2. Clean the area with an alcohol swab.

3. Pinch the skin and insert the needle at a 90-degree angle.

4. Press the plunger until the dose is fully delivered.

Note: Rotate injection sites to prevent skin irritation.

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Trulicity Side Effects

Most side effects are mild and improve over time. Common ones include:

• Nausea (most frequent)

• Diarrhea or vomiting

• Stomach pain

• Decreased appetite

• Fatigue

Serious Side Effects (Seek Medical Help):

• Pancreatitis (severe abdominal pain)

• Kidney problems (changes in urination)

• Severe allergic reactions (rash, swelling, difficulty breathing)

• Low blood sugar (hypoglycemia)—especially when combined with insulin or sulfonylureas

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Who Should Not Take Trulicity?

Trulicity is not recommended for:
❌ People with type 1 diabetes
❌ Those with a history of medullary thyroid carcinoma (MTC)
❌ Patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
❌ Individuals with severe stomach or intestinal problems

Pregnant or breastfeeding women should consult a doctor before use.

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Trulicity vs. Other GLP-1 Agonists

Best for: Patients looking for convenience (once-weekly dosing) and heart protection.

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Trulicity Cost & Savings

• Average price: $900-$1,200 per month (without insurance)

• Savings options:

  • Manufacturer coupons (Lilly Cares)

  • Medicare/Insurance coverage

  • Patient assistance programs

At MediLeanRx, we help patients find affordable Trulicitty alternatives. Contact us for discount options.

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Frequently Asked Questions (FAQs)

1. Does Trulicitty cause weight loss?

Yes! Many patients lose 5-10 lbs due to reduced appetite and slower digestion.

2. Can Trulicitty be taken with metformin?

Yes, Trulicitty is often prescribed alongside metformin for better blood sugar control.

3. How long does Trulicitty stay in your system?

Trulicity has a half-life of ~5 days, meaning it takes about 2-4 weeks to fully leave the body.

4. What happens if I miss a dose?

If you miss a dose, take it within 3 days. If more than 3 days have passed, skip it and resume your next scheduled dose.

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Final Thoughts: Is Trulicity Right for You?

Trulicitty is a powerful, once-weekly GLP-1 agonist that helps manage type 2 diabetes, promotes weight loss, and protects heart health. However, it may not suit everyone—consult your doctor to see if it’s the right choice.

At MediLeanRx, we provide expert guidance on diabetes medications. Get in touch today for personalized advice!

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Why Choose MediLeanRx for Trulicit?

✅ Expert diabetes care
✅ Affordable prescription options
✅ Personalized treatment plans
✅ Fast, reliable service

Visit MediLeanRx.com to learn more!